Triptolide Upregulates Myocardial Forkhead Helix Transcription Factor p3 Expression and Attenuates Cardiac Hypertrophy

• Main Authors: Yuan-Yuan Ding (Author), Jing-Mei Li (Author), Feng-Jie Guo (Author), Ya Liu (Author), Yang-Fei Tong (Author), Xi-Chun Pan (Author), Xiao-Lan Lu (Author), Wen Ye (Author), Xiao-Hong Chen (Author), Hai-Gang Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The forkhead/winged helix transcription factor (Fox) p3 can regulate the expression of various genes, and it has been reported that the transfer of Foxp3-positive T cells could ameliorate cardiac hypertrophy and fibrosis. Triptolide (TP) can elevate the expression of Foxp3, but its effects on cardia...