Solubility enhancement of etoricoxib using inclusion complexation with cyclodextrins: formulation of oro dispersible tablets by QbD approach

• Hauptverfasser: Anjan Kumar Mahapatra (Verfasst von), Siddharth Dora (Verfasst von), Sanatan Parida (Verfasst von), Usharani Bal (Verfasst von), Bandana Rani Jena (Verfasst von), Madhusmita Lenka (Verfasst von)
• Format: Buch
• Veröffentlicht: Creative Pharma Assent, 2024-08-01T00:00:00Z.
• Schlagworte: article
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Background: The work was intended to enhance etoricoxib's solubility and dissolution rate and then develop oro-dispersible tablets for faster onset of action. Methodology: Inclusion complexes (ICs) of the drug were obtained with β-cyclodextrin (β-CD) and hydroxypropyl β-cyclodextrin (HP β-CD) a...