Solubility enhancement of etoricoxib using inclusion complexation with cyclodextrins: formulation of oro dispersible tablets by QbD approach

• Main Authors: Anjan Kumar Mahapatra (Author), Siddharth Dora (Author), Sanatan Parida (Author), Usharani Bal (Author), Bandana Rani Jena (Author), Madhusmita Lenka (Author)
• Format: Book
• Published: Creative Pharma Assent, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The work was intended to enhance etoricoxib's solubility and dissolution rate and then develop oro-dispersible tablets for faster onset of action. Methodology: Inclusion complexes (ICs) of the drug were obtained with β-cyclodextrin (β-CD) and hydroxypropyl β-cyclodextrin (HP β-CD) a...