Polyanhydride Nanoparticle Delivery Platform Dramatically Enhances Killing of Filarial Worms.

• Main Authors: Andrea M Binnebose (Author), Shannon L Haughney (Author), Richard Martin (Author), Paula M Imerman (Author), Balaji Narasimhan (Author), Bryan H Bellaire (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Filarial diseases represent a significant social and economic burden to over 120 million people worldwide and are caused by endoparasites that require the presence of symbiotic bacteria of the genus Wolbachia for fertility and viability of the host parasite. Targeting Wolbachia for elimination is a...