Astaxanthin stimulates mitochondrial biogenesis in insulin resistant muscle via activation of AMPK pathway

• Main Authors: Yasuhiro Nishida (Author), Allah Nawaz (Author), Tomonobu Kado (Author), Akiko Takikawa (Author), Yoshiko Igarashi (Author), Yasuhiro Onogi (Author), Tsutomu Wada (Author), Toshiyasu Sasaoka (Author), Seiji Yamamoto (Author), Masakiyo Sasahara (Author), Johji Imura (Author), Kumpei Tokuyama (Author), Isao Usui (Author), Takashi Nakagawa (Author), Shiho Fujisaka (Author), Yagi Kunimasa (Author), Kazuyuki Tobe (Author)
• Format: Book
• Published: Wiley, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Skeletal muscle is mainly responsible for insulin‐stimulated glucose disposal. Dysfunction in skeletal muscle metabolism especially during obesity contributes to the insulin resistance. Astaxanthin (AX), a natural antioxidant, has been shown to ameliorate hepatic insulin resistan...