Effect of genetic polymorphisms rs2301113 and rs2057482 in the expression of HIF-1α protein in periodontal ligament fibroblasts subjected to compressive force

• Main Authors: Erika Calvano KÜCHLER (Author), Vinicius Broska TEODORO (Author), Agnes SCHRÖDER (Author), Ute NAZET (Author), Michelle Nascimento MEGER (Author), Patricia Valéria Manozzo KUNZ (Author), Flares BARATTO-FILHO (Author), Gerrit SPANIER (Author), Rafaela SCARIOT (Author), Peter PROFF (Author), Christian KIRSCHNECK (Author)
• Format: Book
• Published: University of São Paulo, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Objective Many genes and signaling molecules are involved in orthodontic tooth movement, with mechanically and hypoxically stabilized HIF-1α having been shown to play a decisive role in periodontal ligament signaling during orthodontic tooth movement. Thus, this in vitro study aimed to inve...