Deregulation of the Interleukin-7 Signaling Pathway in Lymphoid Malignancies

The cytokine interleukin-7 (IL-7) and its receptor are critical for lymphoid cell development. The loss of IL-7 signaling causes severe combined immunodeficiency, whereas gain-of-function alterations in the pathway contribute to malignant transformation of lymphocytes. Binding of IL-7 to the IL-7 re...

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Bibliographic Details
Main Authors: Inge Lodewijckx (Author), Jan Cools (Author)
Format: Book
Published: MDPI AG, 2021-05-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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