Peripheral-Type Benzodiazepine Receptor Antagonist Is Effective in Relieving Neuropathic Pain in Mice

• Main Authors: Daisuke Kondo (Author), Hironao Saegusa (Author), Ritsuko Yabe (Author), Ichiro Takasaki (Author), Takashi Kurihara (Author), Shuqin Zong (Author), Tsutomu Tanabe (Author)
• Format: Book
• Published: Elsevier, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract.: cDNA microarray analysis showed the expression of peripheral-type benzodiazepine receptor (PBR) mRNA is slightly enhanced in the spinal cord of mice with spinal nerve injury (SNL) as compared with sham-operated mice. PBR transports cholesterol to the mitochondria, where cholesterol is con...