SNS-032 attenuates liver fibrosis by anti-active hepatic stellate cells via inhibition of cyclin dependent kinase 9

• मुख्य लेखकों: Xiao-Li He (लेखक), Yong-Hong Hu (लेखक), Jia-Mei Chen (लेखक), Ding-Qi Zhang (लेखक), Hai-Lin Yang (लेखक), Lin-Zhang Zhang (लेखक), Yong-Ping Mu (लेखक), Hua Zhang (लेखक), Gao-Feng Chen (लेखक), Wei Liu (लेखक), Ping Liu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Liver fibrosis is a common pathological process of all chronic liver diseases. Hepatic stellate cells (HSCs) play a central role in the development of liver fibrosis. Cyclin-dependent kinase 9 (CDK9) is a cell cycle kinase that regulates mRNA transcription and elongation. A CDK9 inhibitor SNS-032 ha...