First studies on tumor associated carbonic anhydrases IX and XII monoclonal antibodies conjugated to small molecule inhibitors

We report for the first time Antibody-Drug-Conjugates (ADCs) containing human (h) Carbonic Anhydrase (CA; EC 4.2.1.1) directed Monoclonal Antibodies (MAbs) linked to low molecular weight inhibitors of the same enzymes by means of hydrophilic peptide spacers. In agreement with the incorporated CA dir...

Full description

Saved in:
Bibliographic Details
Main Authors: Chiara Testa (Author), Anna Maria Papini (Author), Reinhard Zeidler (Author), Daniela Vullo (Author), Fabrizio Carta (Author), Claudiu T. Supuran (Author), Paolo Rovero (Author)
Format: Book
Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available