Synthesis and Preliminary Anticancer Evaluation of 6-Mercaptopurine -Methotrexate Conjugate as Possible Mutual Prodrug

Small molecules drug conjugate mutual prodrug design  (SMDC) composed of folate and lethal agent conjugate, rigidly bonded via hydrophilic bridge and self immolative disulfide  bond   ;  represent new interesting approaches for cancer treatment , the component of SMDC intended  for targeting    fola...

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Main Authors: Asmaa S. Al-Darraji (Author), Mohamed H.Mohamed (Author)
Format: Knjiga
Izdano: College of Pharmacy University of Baghdad, 2019-06-01T00:00:00Z.
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