Epigallocatechin-3-Gallate Plus Omega-3 Restores the Mitochondrial Complex I and F₀F₁-ATP Synthase Activities in PBMCs of Young Children with Down Syndrome: A Pilot Study of Safety and Efficacy

• প্রধান লেখক: Iris Scala (লেখক), Daniela Valenti (লেখক), Valentina Scotto D'Aniello (লেখক), Maria Marino (লেখক), Maria Pia Riccio (লেখক), Carmela Bravaccio (লেখক), Rosa Anna Vacca (লেখক), Pietro Strisciuglio (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2021-03-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Down syndrome (DS) is a major genetic cause of intellectual disability. DS pathogenesis has not been fully elucidated, and no specific pharmacological therapy is available. DYRK1A overexpression, oxidative stress and mitochondrial dysfunction were described in trisomy 21. Epigallocatechin-3-gallate...