Regulation of microRNA biosynthesis and expression in 2102Ep embryonal carcinoma stem cells is mirrored in ovarian serous adenocarcinoma patients

• Main Authors: Gallagher Michael F (Author), Flavin Richard J (Author), Elbaruni Salah A (Author), McInerney Jamie K (Author), Smyth Paul C (Author), Salley Yvonne M (Author), Vencken Sebastian F (Author), O'Toole Sharon A (Author), Laios Alexandros (Author), Lee Mathia YC (Author), Denning Karen (Author), Li Jinghuan (Author), Aherne Sinead T (Author), Lao Kai Q (Author), Martin Cara M (Author), Sheils Orla M (Author), O'Leary John J (Author)
• Format: Book
• Published: BMC, 2009-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Tumours with high proportions of differentiated cells are considered to be of a lower grade to those containing high proportions of undifferentiated cells. This property may be linked to the differentiation properties of stem cell-li...