Astatine-211-Labeled Gold Nanoparticles for Targeted Alpha-Particle Therapy via Intravenous Injection

• Main Authors: Xuhao Huang (Author), Kazuko Kaneda-Nakashima (Author), Yuichiro Kadonaga (Author), Kazuya Kabayama (Author), Atsushi Shimoyama (Author), Kazuhiro Ooe (Author), Hiroki Kato (Author), Atsushi Toyoshima (Author), Atsushi Shinohara (Author), Hiromitsu Haba (Author), Yang Wang (Author), Koichi Fukase (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alpha-particle radiotherapy has gained considerable attention owing to its potent anti-cancer effect. ²¹¹At, with a relatively short half-life of 7.2 h, emits an alpha particle within a few cell diameters with high kinetic energy, which damages cancer cells with high biologica...