Microwave-Assisted, One-Pot Synthesis of Doxycycline under Heterogeneous Catalysis in Water

• Main Authors: Fabio Bucciol (Author), Elia Maffeis (Author), Emanuela Calcio Gaudino (Author), László Jicsinszky (Author), Silvia Tagliapietra (Author), Alessandro Barge (Author), Cristina Prandi (Author), Giancarlo Cravotto (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The selective synthesis of active pharmaceutical molecules is a challenging issue, particularly when attempting to make the reactions even more sustainable. The present work focuses on the microwave-assisted hydrogenolysis of oxytetracycline to selectively produce α-doxycycline. Although the combina...