An integrated approach for characterizing immunogenic responses toward a bispecific antibody

• Main Authors: Sivan Cohen (Author), Shan Chung (Author), Christoph Spiess (Author), Victor Lundin (Author), Eric Stefanich (Author), Steven T. Laing (Author), Vanessa Clark (Author), Jochen Brumm (Author), Ying Zhou (Author), Catherine Huang (Author), Joyce Guerrero (Author), Srividya Myneni (Author), Rajbharan Yadav (Author), Ketevan Siradze (Author), Kun Peng (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bispecific antibodies (bsAbs) recognize and bind two different targets or two epitopes of the same antigen, making them an attractive diagnostic and treatment modality. Compared to the production of conventional bivalent monospecific antibodies, bsAbs require greater engineering and manufacturing. T...