Ginsenoside Rb1 and Rd Remarkably Inhibited the Hepatic Uptake of Ophiopogonin D in Shenmai Injection Mediated by OATPs/oatps

• Autors principals: Xiaopei Liu (Autor), Lin Chen (Autor), Mingyi Liu (Autor), Hong Zhang (Autor), Shibo Huang (Autor), Yuqing Xiong (Autor), Chunhua Xia (Autor)
• Format: Llibre
• Publicat: Frontiers Media S.A., 2018-08-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Shenmai injection (SMI) is derived from traditional Chinese herbal prescription Shendong yin and widely used for treating cardiovascular diseases. Ophiopogonin D (OPD) is one of the main active components of SMI. The hepatic uptake of OPD is mediated by organic anion-transporting polypeptides (OATPs...