Ginsenoside Rb1 and Rd Remarkably Inhibited the Hepatic Uptake of Ophiopogonin D in Shenmai Injection Mediated by OATPs/oatps

• Main Authors: Xiaopei Liu (Author), Lin Chen (Author), Mingyi Liu (Author), Hong Zhang (Author), Shibo Huang (Author), Yuqing Xiong (Author), Chunhua Xia (Author)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2018-08-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Shenmai injection (SMI) is derived from traditional Chinese herbal prescription Shendong yin and widely used for treating cardiovascular diseases. Ophiopogonin D (OPD) is one of the main active components of SMI. The hepatic uptake of OPD is mediated by organic anion-transporting polypeptides (OATPs...