HMGA2 regulation by miRNAs in cancer: Affecting cancer hallmarks and therapy response

• Main Authors: Mehrdad Hashemi (Author), Mohsen Rashidi (Author), Kiavash Hushmandi (Author), Timo L.M. ten Hagen (Author), Shokooh Salimimoghadam (Author), Afshin Taheriazam (Author), Maliheh Entezari (Author), Mojtaba Falahati (Author)
• Format: Book
• Published: Elsevier, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

High mobility group A 2 (HMGA2) is a protein that modulates the structure of chromatin in the nucleus. Importantly, aberrant expression of HMGA2 occurs during carcinogenesis, and this protein is an upstream mediator of cancer hallmarks including evasion of apoptosis, proliferation, invasion, metasta...