Optimized New Shengmai Powder modulation of cAMP/Rap1A signaling pathway attenuates myocardial fibrosis in heart failure

• Main Authors: Zeyu Zhang (Author), Zhe xu (Author), Shuai Wang (Author), Zhuangzhuang Jia (Author), Zhou zhou (Author), Ci Wang (Author), Shanshan Lin (Author), Yiting Feng (Author), Xianliang Wang (Author), Jingyuan Mao (Author)
• Format: Book
• Published: BMC, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Optimized New Shengmai Powder (ONSMP) is a traditional Chinese medicine formula with significant anti-heart failure and myocardial fibrosis effects, but the specific molecular biological mechanisms are not fully understood. Methods In this study, we first used network pharmacolog...