Structures Illuminate Cardiac Ion Channel Functions in Health and in Long QT Syndrome

• Autores principales: Kathryn R. Brewer (Autor), Georg Kuenze (Autor), Carlos G. Vanoye (Autor), Alfred L. George (Autor), Jens Meiler (Autor), Charles R. Sanders (Autor)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

The cardiac action potential is critical to the production of a synchronized heartbeat. This electrical impulse is governed by the intricate activity of cardiac ion channels, among them the cardiac voltage-gated potassium (Kv) channels KCNQ1 and hERG as well as the voltage-gated sodium (Nav) channel...