Anti-inflammatory efficacy of Berberine Nanomicelle for improvement of cerebral ischemia: formulation, characterization and evaluation in bilateral common carotid artery occlusion rat model

• Glavni autori: Roza Azadi (Autor), Seyyedeh Elaheh Mousavi (Autor), Negar Motakef Kazemi (Autor), Hasan Yousefi-Manesh (Autor), Seyed Mahdi Rezayat (Autor), Mahmoud Reza Jaafari (Autor)
• Format: Knjiga
• Izdano: BMC, 2021-10-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Abstract Background Berberine (BBR) is a plant alkaloid that possesses anti-inflammatory and anti-oxidant effects with low oral bioavailability. In this study, micelle formulation of BBR was investigated to improve therapeutic efficacy and examined its effect on the secretion of inflammatory cytokin...