Anti-inflammatory efficacy of Berberine Nanomicelle for improvement of cerebral ischemia: formulation, characterization and evaluation in bilateral common carotid artery occlusion rat model

• Auteurs principaux: Roza Azadi (Auteur), Seyyedeh Elaheh Mousavi (Auteur), Negar Motakef Kazemi (Auteur), Hasan Yousefi-Manesh (Auteur), Seyed Mahdi Rezayat (Auteur), Mahmoud Reza Jaafari (Auteur)
• Format: Livre
• Publié: BMC, 2021-10-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Abstract Background Berberine (BBR) is a plant alkaloid that possesses anti-inflammatory and anti-oxidant effects with low oral bioavailability. In this study, micelle formulation of BBR was investigated to improve therapeutic efficacy and examined its effect on the secretion of inflammatory cytokin...