Human macrophage response to L. (Viannia) panamensis: microarray evidence for an early inflammatory response.

• Main Authors: Carolina Ramírez (Author), Yira Díaz-Toro (Author), Jair Tellez (Author), Tiago M Castilho (Author), Ricardo Rojas (Author), Nicholas A Ettinger (Author), Irina Tikhonova (Author), Neal D Alexander (Author), Liliana Valderrama (Author), Janet Hager (Author), Mary E Wilson (Author), Aiping Lin (Author), Hongyu Zhao (Author), Nancy G Saravia (Author), Diane McMahon-Pratt (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Previous findings indicate that susceptibility to Leishmania (Viannia) panamensis infection of monocyte-derived macrophages from patients and asymptomatically infected individuals were associated with the adaptive immune response and clinical outcome. METHODOLOGY/PRINCIPAL FINDINGS:To und...