Computer-aided laser dissection: A microdissection workflow leveraging image analysis tools

• Main Authors: Jason D Hipp (Author), Donald J Johann (Author), Yun Chen (Author), Anant Madabhushi (Author), James Monaco (Author), Jerome Cheng (Author), Jaime Rodriguez-Canales (Author), Martin C Stumpe (Author), Greg Riedlinger (Author), Avi Z Rosenberg (Author), Jeffrey C Hanson (Author), Lakshmi P Kunju (Author), Michael R Emmert-Buck (Author), Ulysses J Balis (Author), Michael A Tangrea (Author)
• Format: Book
• Published: Elsevier, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: The development and application of new molecular diagnostic assays based on next-generation sequencing and proteomics require improved methodologies for procurement of target cells from histological sections. Laser microdissection can successfully isolate distinct cells from tissue spe...