The journey of canakinumab; on- and off-label indications

• मुख्य लेखकों: Daniela Marotto (लेखक), Alberto Batticciotto (लेखक), Angela Ceribelli (लेखक), Piercarlo Sarzi Puttini (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Verduci Editore, 2019-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The role of interleukin-1 (IL-1) has been studied in many diseases, ranging from auto-inflammatory diseases to malignancies, and much has been discovered. There are currently four IL-1 inhibitors available, but only two have been approved in Europe: the receptor antagonist anakinra, and the IL-1b se...