Convergence of dopamine and glutamate signalling onto striatal ERK activation in response to drugs of abuse.
Despite their distinct targets, all addictive drugs commonly abused by humans evoke increases in dopamine (DA) concentration within the striatum. The main DA G-Protein Coupled Receptors (GPCRs) expressed by medium-sized spiny neurons (MSNs) of the striatum are the D1R and D2R, which are positively a...
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| Main Authors: | , , , |
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| Format: | Book |
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Frontiers Media S.A.,
2014-01-01T00:00:00Z.
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