Amelioration by the Natural Polyamine Spermine of Cartilage and Bone Destruction in Rats With Collagen-Induced Arthritis

We investigated pharmacological properties of naturally occurring polyamines on cartilage and bone destruction seen in joints of rats with collagen-induced arthritis (CIA). Daily supplementation of spermine (SPM), but not spermidine, significantly inhibited increases in the hind paw volume and arthr...

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Príomhchruthaitheoirí: Takashi Iezaki (Údar), Eiichi Hinoi (Údar), Tomomi Yamamoto (Údar), Ryo Ishiura (Údar), Shinya Ogawa (Údar), Yukio Yoneda (Údar)
Formáid: LEABHAR
Foilsithe / Cruthaithe: Elsevier, 2012-01-01T00:00:00Z.
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