Predictive Testing for Tumor Predisposition Syndromes in Pediatric Relatives: An Asian Experience

• Hoofdauteurs: Jianbang Chiang (Auteur), Jeanette Yuen (Auteur), Tarryn Shaw (Auteur), Hui Xuan Goh (Auteur), Shao-Tzu Li (Auteur), Eliza Courtney (Auteur), Joanne Ngeow (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2020-10-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Approximately 10% of pediatric cancer patients possess germline pathogenic/likely pathogenic variants (PV/LPV) in known tumor predisposition genes. Predictive testing is the optimal approach to identify asymptomatic at-risk relatives to guide gene-directed surveillance for early cancer detection and...