Systemic FasL and TRAIL neutralisation reduce leishmaniasis induced skin ulceration.

• Main Authors: Geremew Tasew (Author), Susanne Nylén (Author), Thorsten Lieke (Author), Befekadu Lemu (Author), Hailu Meless (Author), Nicolas Ruffin (Author), Dawit Wolday (Author), Abraham Asseffa (Author), Hideo Yagita (Author), Sven Britton (Author), Hannah Akuffo (Author), Francesca Chiodi (Author), Liv Eidsmo (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cutaneous leishmaniasis (CL) is caused by Leishmania infection of dermal macrophages and is associated with chronic inflammation of the skin. L. aethiopica infection displays two clinical manifestations, firstly ulcerative disease, correlated to a relatively low parasite load in the skin, and second...