Harpagoside attenuates local bone Erosion and systemic osteoporosis in collagen-induced arthritis in mice

• Main Authors: Ju-Young Kim (Author), Yoon-Hee Cheon (Author), Sung-Jun Ahn (Author), Sung Chul Kwak (Author), Chong Hyuk Chung (Author), Chang Hoon Lee (Author), Myeung Su Lee (Author)
• Format: Book
• Published: BMC, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that causes local bone erosion and systemic osteoporosis. Harpagoside (HAR), an iridoid glycoside, has various pharmacological effects on pain, arthritis, and inflammation. Our previous study suggests that HAR...