Development and characterization of liposomal formulation of bortezomib

• Main Authors: Anil K. Deshantri (Author), Josbert M. Metselaar (Author), Stavroula Zagkou (Author), Gert Storm (Author), Sanjay N. Mandhane (Author), Marcel H.A.M. Fens (Author), Raymond M. Schiffelers (Author)
• Format: Book
• Published: Elsevier, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bortezomib is a proteasome inhibitor used for the treatment of multiple myeloma. The poor pharmacokinetic profile and off-target adverse effects provide a strong incentive to develop drug delivery systems for bortezomib. In the past, liposomal encapsulation has been proven to improve the therapeutic...