Zingiber officinale Roscoe extract improves nigrostriatal dopaminergic activity in rotenone-induced Parkinsonian mice: Implication of COX-2/TNF-α/IL-6 and antioxidant enzyme crosstalk in the immunoinflammatory responses

• Main Authors: Olusegun G. Adebayo (Author), Benneth Ben-Azu (Author), Egwonor Akpofure (Author), Emmanuel U. Modo (Author), Iheangwam Pauline Ndidiamaka (Author), Joseph Igbo Enya (Author), Favor Akpakpan Udoeyop (Author), Benjamin Oritsemuelebi (Author), Emmanuel O. Chidebe (Author), Joseph Chimezie (Author), Noah A. Omeiza (Author), Jerome Ndudi Asiwe (Author), Silver Isosiya Davies (Author), Samuel A. Onasanwo (Author)
• Format: Book
• Published: Elsevier, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ethnopharmacological relevance: Parkinson's disease (PD) is a chronic neurodegenerative disease that occurs progressively with time. Current PD treatments are symptomatic with moderate effects on striatal dopamine release. Previously, the ethnomedicinal benefits of Zingiber officinale Roscoe ha...