Thiosemicarbazones and selected tyrosine kinase inhibitors synergize in pediatric solid tumors: NDRG1 upregulation and impaired prosurvival signaling in neuroblastoma cells

Tyrosine kinase inhibitors (TKIs) are frequently used in combined therapy to enhance treatment efficacy and overcome drug resistance. The present study analyzed the effects of three inhibitors, sunitinib, gefitinib, and lapatinib, combined with iron-chelating agents, di-2-pyridylketone-4,4-dimethyl-...

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Main Authors: Maria Krchniakova (Author), Silvia Paukovcekova (Author), Petr Chlapek (Author), Jakub Neradil (Author), Jan Skoda (Author), Renata Veselska (Author)
Format: Book
Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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