A Newborn Screening Program for Sickle Cell Disease in Murcia (Spain)

• Main Authors: María Sánchez-Villalobos (Author), Eulalia Campos Baños (Author), María Jesús Juan Fita (Author), José María Egea Mellado (Author), Inmaculada Gonzalez Gallego (Author), Asunción Beltrán Videla (Author), Mercedes Berenguer Piqueras (Author), Mar Bermúdez Cortés (Author), José María Moraleda Jiménez (Author), Encarna Guillen Navarro (Author), Eduardo Salido Fierrez (Author), Ana B. Pérez-Oliva (Author)
• Format: Book
• Published: MDPI AG, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sickle cell disease (SCD) is an inherited autosomal recessive hemoglobin disorder caused by the presence of hemoglobin S, a mutant abnormal hemoglobin caused by a nucleotide change in codon 6 of the β-globin chain gene. SCD involves a chronic inflammatory state, exacerbated during vaso-occlusive cri...