Self-emulsifying micelles as a drug nanocarrier system for itraconazole oral bioavailability enhancement; in vitro and in vivo assessment

• Main Authors: Nayyer Islam (Author), Naveed Ullah Khan (Author), Anam Razzaq (Author), Zaheer Ullah Khan (Author), Farid Menaa (Author), Mohammad Y. Alfaifi (Author), Serag Eldin I. Elbehairi (Author), Haroon Iqbal (Author), Jiang Ni (Author)
• Format: Book
• Published: Elsevier, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Itraconazole (ITZ) is a renowned antifungal medication, however its therapeutic efficacy is limited by low solubility and oral bioavailability. The current research work attempted to augment the oral bioavailability of ITZ by incorporating into self-emulsifying micelles (SEMCs). To fabricate the SEM...