Subconjunctival Delivery of Sorafenib-Tosylate-Loaded Cubosomes for Facilitated Diabetic Retinopathy Treatment: Formulation Development, Evaluation, Pharmacokinetic and Pharmacodynamic (PKPD) Studies

Subconjunctival Delivery of Sorafenib-Tosylate-Loaded Cubosomes for Facilitated Diabetic Retinopathy Treatment: Formulation Development, Evaluation, Pharmacokinetic and Pharmacodynamic (PKPD) Studies

Diabetic retinopathy (DR) is a microvascular complication associated with vascular endothelial growth factor (VEGF) overexpression. Therapeutic delivery to the retina is a challenging phenomenon due to ocular biological barriers. Sorafenib tosylate (ST) is a lipophilic drug with low molecular weight...

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Main Authors: Sharadha Madhusudhan (Author), Naresh Vishal Gupta (Author), Mohamed Rahamathulla (Author), Saravana Babu Chidambaram (Author), Riyaz Ali M. Osmani (Author), Mohammed Ghazwani (Author), Mohammed Muqtader Ahmed (Author), Syeda Ayesha Farhana (Author), Mohammed Y. Sarhan (Author), Ahmed Hediyal Tousif (Author)
Format: Book
Published: MDPI AG, 2023-10-01T00:00:00Z.
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