Natural inspired piperine-based ureas and amides as novel antitumor agents towards breast cancer

• Auteurs principaux: Diaaeldin M. Elimam (Auteur), Abdullah A. Elgazar (Auteur), Fardous F. El-Senduny (Auteur), Ramadan A. El-Domany (Auteur), Farid A Badria (Auteur), Wagdy M. Eldehna (Auteur)
• Format: Livre
• Publié: Taylor & Francis Group, 2022-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

In this work, the natural piperine moiety was utilised to develop two sets of piperine-based amides (5a-i) and ureas (8a-y) as potential anticancer agents. The anticancer action was assessed against triple negative breast cancer (TNBC) MDA-MB-231, ovarian A2780CP and hepatocellular HepG2 cancer cell...