A study of the average effect of the 3'APOB-VNTR polymorphism on lipidemic parameters could explain why the short alleles (<35 repeats) are rare in centenarians

• Main Authors: Mari Vincenzo (Author), DeRango Francesco (Author), Berardelli Maurizio (Author), Garasto Sabrina (Author), Feraco Emidio (Author), De Benedictis Giovanna (Author)
• Format: Book
• Published: BMC, 2004-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>In studies on the genetics of human aging, we observed an age-related variation of the 3'APOB-VNTR genotypic pool (alleles: <it>Short</it>, <it>S</it>, <35 repeats; <it>Medium</it>, <it&...