Magnetic resonance imaging and ultrasound elastography in the context of preclinical pharmacological research: significance for the 3R principles

• Asıl Yazarlar: Michael Obrecht (Yazar), Stefan Zurbruegg (Yazar), Nathalie Accart (Yazar), Christian Lambert (Yazar), Arno Doelemeyer (Yazar), Birgit Ledermann (Yazar), Nicolau Beckmann (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2023-06-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The 3Rs principles-reduction, refinement, replacement-are at the core of preclinical research within drug discovery, which still relies to a great extent on the availability of models of disease in animals. Minimizing their distress, reducing their number as well as searching for means to replace th...