Orally administered intelligent self-ablating nanoparticles: a new approach to improve drug cellular uptake and intestinal absorption

• Main Authors: Yanzi Liang (Author), Ruihuan Ding (Author), Huihui Wang (Author), Lanze Liu (Author), Jibiao He (Author), Yuping Tao (Author), Zhenyu Zhao (Author), Jie Zhang (Author), Aiping Wang (Author), Kaoxiang Sun (Author), Youxin Li (Author), Yanan Shi (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oral drug delivery to treat diabetes is being increasingly researched. The mucus and the epithelial cell layers hinder drug delivery. We designed a self-ablating nanoparticle to achieve smart oral delivery to overcome the gastrointestinal barrier. We used the zwitterionic dilauroyl phosphatidylcholi...