Biphasic Dissolution as an Exploratory Method during Early Drug Product Development

• Автори: Daniela Amaral Silva (Автор), Jozef Al-Gousous (Автор), Neal M. Davies (Автор), Nadia Bou Chacra (Автор), Gregory K. Webster (Автор), Elke Lipka (Автор), Gordon L. Amidon (Автор), Raimar Löbenberg (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2020-05-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Dissolution testing is a major tool used to assess a drug product's performance and as a quality control test for solid oral dosage forms. However, compendial equipment and methods may lack discriminatory power and the ability to simulate aspects of in vivo dissolution. Using low buffer capacit...