Biphasic Dissolution as an Exploratory Method during Early Drug Product Development

• मुख्य लेखकों: Daniela Amaral Silva (लेखक), Jozef Al-Gousous (लेखक), Neal M. Davies (लेखक), Nadia Bou Chacra (लेखक), Gregory K. Webster (लेखक), Elke Lipka (लेखक), Gordon L. Amidon (लेखक), Raimar Löbenberg (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2020-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Dissolution testing is a major tool used to assess a drug product's performance and as a quality control test for solid oral dosage forms. However, compendial equipment and methods may lack discriminatory power and the ability to simulate aspects of in vivo dissolution. Using low buffer capacit...