Statistical driver genes as a means to uncover missing heritability for age-related macular degeneration

• Main Authors: Andrea R. Waksmunski (Author), Michelle Grunin (Author), Tyler G. Kinzy (Author), Robert P. Igo (Author), Jonathan L. Haines (Author), Jessica N. Cooke Bailey (Author)
• Format: Book
• Published: BMC, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Age-related macular degeneration (AMD) is a progressive retinal disease contributing to blindness worldwide. Multiple estimates for AMD heritability (h 2 ) exist; however, a substantial proportion of h 2 is not attributable to known genomic loci. The International AMD Genomics Co...