CRISPR/Cas9-loxP-Mediated Gene Editing as a Novel Site-Specific Genetic Manipulation Tool

• Main Authors: Fayu Yang (Author), Changbao Liu (Author), Ding Chen (Author), Mengjun Tu (Author), Haihua Xie (Author), Huihui Sun (Author), Xianglian Ge (Author), Lianchao Tang (Author), Jin Li (Author), Jiayong Zheng (Author), Zongming Song (Author), Jia Qu (Author), Feng Gu (Author)
• Format: Book
• Published: Elsevier, 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cre-loxP, as one of the site-specific genetic manipulation tools, offers a method to study the spatial and temporal regulation of gene expression/inactivation in order to decipher gene function. CRISPR/Cas9-mediated targeted genome engineering technologies are sparking a new revolution in biological...