Supratherapeutic dose evaluation and effect of lesinurad on cardiac repolarization: a thorough QT/QTc study

• Main Authors: Shen Z (Author), Gillen M (Author), Tieu K (Author), Nguyen M (Author), Harmon E (Author), Wilson DM (Author), Kerr B (Author), Lee CA (Author)
• Format: Book
• Published: Dove Medical Press, 2016-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Zancong Shen,1 Michael Gillen,2 Kathy Tieu,1 Mai Nguyen,1 Erin Harmon,1 David M Wilson,1 Bradley Kerr,1 Caroline A Lee1 1Ardea Biosciences, Inc., San Diego, CA, 2AstraZeneca LP, Gaithersburg, MD, USA Introduction: Lesinurad is a selective uric acid reabsorption inhibitor approved in the United State...