Nonviral Direct Conversion of Primary Mouse Embryonic Fibroblasts to Neuronal Cells

• Main Authors: Andrew F Adler (Author), Christopher L Grigsby (Author), Karina Kulangara (Author), Hong Wang (Author), Ryohei Yasuda (Author), Kam W Leong (Author)
• Format: Book
• Published: Elsevier, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Transdifferentiation, where differentiated cells are reprogrammed into another lineage without going through an intermediate proliferative stem cell-like stage, is the next frontier of regenerative medicine. Wernig et al. first described the direct conversion of fibroblasts into functional induced n...