Integrative Human Genetic and Cellular Analysis of the Pathophysiological Roles of AnxA2 in Alzheimer's Disease

• Main Authors: Lianmeng Ye (Author), Jiazheng Zhao (Author), Zhengpan Xiao (Author), Wenyu Gu (Author), Xiaoxuan Liu (Author), Nuela Manka'a Che Ajuyo (Author), Yi Min (Author), Yechun Pei (Author), Dayong Wang (Author)
• Format: Book
• Published: MDPI AG, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alzheimer's disease (AD) is an intractable and progressive neurodegenerative disease. Amyloid beta (Aβ) aggregation is the hallmark of AD. Aβ induces neurotoxicity through a variety of mechanisms, including interacting with membrane receptors to alter downstream signaling, damaging cellular or...