Endocannabinoid and nitric oxide systems of the hypothalamic paraventricular nucleus mediate effects of NPY on energy expenditure

• Main Authors: Zoltán Péterfi (Author), Imre Farkas (Author), Raphael G.P. Denis (Author), Erzsébet Farkas (Author), Motokazu Uchigashima (Author), Tamás Füzesi (Author), Masahiko Watanabe (Author), Ronald M. Lechan (Author), Zsolt Liposits (Author), Serge Luquet (Author), Csaba Fekete (Author)
• Format: Book
• Published: Elsevier, 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Neuropeptide Y (NPY) is one of the most potent orexigenic peptides. The hypothalamic paraventricular nucleus (PVN) is a major locus where NPY exerts its effects on energy homeostasis. We investigated how NPY exerts its effect within the PVN. Methods: Patch clamp electrophysiology and Ca2+...