Expanding the toolbox of metabolically stable lipid prodrug strategies

• Autori principali: Kiran S. Toti (Autore), Nicole Pribut (Autore), Michael D'Erasmo (Autore), Madhuri Dasari (Autore), Savita K. Sharma (Autore), Perry W. Bartsch (Autore), Samantha L. Burton (Autore), Hannah B. Gold (Autore), Anatoliy Bushnev (Autore), Cynthia A. Derdeyn (Autore), Adriaan E. Basson (Autore), Dennis C. Liotta (Autore), Eric J. Miller (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Nucleoside- and nucleotide-based therapeutics are indispensable treatment options for patients suffering from malignant and viral diseases. These agents are most commonly administered to patients as prodrugs to maximize bioavailability and efficacy. While the literature provides a practical prodrug...