Swietephragmin D, a limonoid from Swietenia mahagoni, reverses multidrug resistance by inhibiting P-glycoprotein dependent efflux

• Κύριοι συγγραφείς: Han Guo (Συγγραφέας), Sheng Gao (Συγγραφέας), Yifan Zhu (Συγγραφέας), Yuanqiang Guo (Συγγραφέας), Zheng Hou (Συγγραφέας), Yonggang Ma (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Elsevier, 2022-05-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Background: : P-glycoprotein mediated efflux leads to multidrug resistance of tumor cells, which is an important reason for chemotherapy failure. Thus inhibiting P-gp is an effective approach to reverse multidrug resistance. Purpose: : Swietephragmin D is a limonoid compound isolated from the fruits...