THE ASSOCIATION OF MATERNAL HLA-DRB1* WITH RISK OF DEVELOPMENT CONGENITAL SEPTAL HEART DEFECTS AT THEIR CHILDREN

• Main Authors: Андрей Владимирович Шабалдин (Author), Анна Викторовна Цепокина (Author), Надежда Алексеевна Литвинова (Author), Светлана Александровна Шмулевич (Author), Павел Михайлович Крюков (Author)
• Format: Book
• Published: The Publishing House Medicine and Enlightenment, 2016-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

HLA-DR locus includes immune response genes (Ir), which are controlled by thymus-dependent immune responses to endobiotiki and xenon. In pregnancy, maternal microenvironment Ir genes may determine the effectiveness of the protection of the embryo and fetus by teratogens. Accordingly, the purpose of...